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mRNA Translocation Occurs During the Second Step of Ribosomal Intersubunit Rotation

During protein synthesis, mRNA and tRNA undergo coupled translocation through the ribosome in a process that is catalyzed by elongation factor EF-G. Based on cryo-EM reconstructions, counterclockwise and clockwise rotational movements between the large and small ribosomal subunits have been implicat...

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Autors principals: Ermolenko, Dmitri N., Noller, Harry F.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079290/
https://ncbi.nlm.nih.gov/pubmed/21399643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2011
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