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Rotation of the head of the 30S ribosomal subunit during mRNA translocation

Elongation factor-G–catalyzed translocation of mRNA and tRNAs during protein synthesis involves large-scale conformational changes in the ribosome. Formation of hybrid-state intermediates is coupled to counterclockwise (forward) rotation of the body of the 30S subunit. Recent structural studies impl...

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Detalles Bibliográficos
Main Authors: Guo, Zhuojun, Noller, Harry F.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528506/
https://ncbi.nlm.nih.gov/pubmed/23188795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218999109
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