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Antibiotics that bind to the A site of the large ribosomal subunit can induce mRNA translocation
In the absence of elongation factor EF-G, ribosomes undergo spontaneous, thermally driven fluctuation between the pre-translocation (classical) and intermediate (hybrid) states of translocation. These fluctuations do not result in productive mRNA translocation. Extending previous findings that the a...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3543091/ https://ncbi.nlm.nih.gov/pubmed/23249745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.035964.112 |
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