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Spontaneous Intersubunit Rotation in Single Ribosomes

During the elongation cycle, tRNA and mRNA undergo coupled translocation through the ribosome catalyzed by elongation factor EF-G. Cryo-EM reconstructions of certain EF-G-containing complexes led to the proposal that the mechanism of translocation involves rotational movement between the two ribosom...

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Autors principals: Cornish, Peter V., Ermolenko, Dmitri N., Noller, Harry F., Ha, Taekjip
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491453/
https://ncbi.nlm.nih.gov/pubmed/18538656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.05.004
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