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Spontaneous Intersubunit Rotation in Single Ribosomes

During the elongation cycle, tRNA and mRNA undergo coupled translocation through the ribosome catalyzed by elongation factor EF-G. Cryo-EM reconstructions of certain EF-G-containing complexes led to the proposal that the mechanism of translocation involves rotational movement between the two ribosom...

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Bibliographic Details
Main Authors: Cornish, Peter V., Ermolenko, Dmitri N., Noller, Harry F., Ha, Taekjip
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491453/
https://ncbi.nlm.nih.gov/pubmed/18538656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.05.004
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