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Translation of the poly(A) tail plays crucial roles in nonstop mRNA surveillance via translation repression and protein destabilization by proteasome in yeast

mRNA surveillance system represses the expression of nonstop mRNA by rapid mRNA degradation and translation repression. Here we show that the level of protein product of nonstop mRNA containing a poly(A) tail was reduced 100-fold, and this reduction was due to rapid mRNA degradation, translation rep...

詳細記述

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書誌詳細
主要な著者: Ito-Harashima, Sayoko, Kuroha, Kazushige, Tatematsu, Tsuyako, Inada, Toshifumi
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820893/
https://ncbi.nlm.nih.gov/pubmed/17344413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1490207
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