Receptor for activated C kinase 1 stimulates nascent polypeptide-dependent translation arrest

Nascent peptide-dependent translation arrest is crucial for the quality control of eukaryotic gene expression. Here we show that the receptor for activated C kinase 1 (RACK1) participates in nascent peptide-dependent translation arrest, and that its binding to the 40S subunit is crucial for this. Tr...

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Autors principals: Kuroha, Kazushige, Akamatsu, Mayuko, Dimitrova, Lyudmila, Ito, Takehiko, Kato, Yuki, Shirahige, Katsuhiko, Inada, Toshifumi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
Matèries:
Scientific Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999862/
https://ncbi.nlm.nih.gov/pubmed/21072063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.169
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