Structural Insight Into Nascent Polypeptide Chain-Mediated Translational Stalling

Expression of the Escherichia coli tryptophanase operon depends upon ribosome stalling during translation of the upstream TnaC leader peptide, a process for which interactions between the TnaC nascent chain and the ribosomal exit tunnel are critical. We determined a 5.8 Å resolution cryo-electron mi...

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Autores principales: Seidelt, Birgit, Innis, C. Axel, Wilson, Daniel N., Gartmann, Marco, Armache, Jean-Paul, Villa, Elizabeth, Trabuco, Leonardo G., Becker, Thomas, Mielke, Thorsten, Schulten, Klaus, Steitz, Thomas A., Beckmann, Roland
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920484/
https://ncbi.nlm.nih.gov/pubmed/19933110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1177662
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