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Mechanisms of SecM-Mediated Stalling in the Ribosome

Nascent-peptide modulation of translation is a common regulatory mechanism of gene expression. In this mechanism, while the nascent peptide is still in the exit tunnel of the ribosome, it induces translational pausing, thereby controlling the expression of downstream genes. One example is SecM, whic...

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Main Authors: Gumbart, James, Schreiner, Eduard, Wilson, Daniel N., Beckmann, Roland, Schulten, Klaus
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400775/
https://ncbi.nlm.nih.gov/pubmed/22853911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.005
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