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Mechanisms of SecM-Mediated Stalling in the Ribosome

Nascent-peptide modulation of translation is a common regulatory mechanism of gene expression. In this mechanism, while the nascent peptide is still in the exit tunnel of the ribosome, it induces translational pausing, thereby controlling the expression of downstream genes. One example is SecM, whic...

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Detalhes bibliográficos
Main Authors: Gumbart, James, Schreiner, Eduard, Wilson, Daniel N., Beckmann, Roland, Schulten, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400775/
https://ncbi.nlm.nih.gov/pubmed/22853911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.005
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