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SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center

As nascent polypeptide chains are synthesized, they pass through a tunnel in the large ribosomal subunit. Interaction between specific nascent chains and the ribosomal tunnel is used to induce translational stalling for the regulation of gene expression. One well-characterized example is the Escheri...

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Detalhes bibliográficos
Main Authors: Bhushan, Shashi, Hoffmann, Thomas, Seidelt, Birgit, Frauenfeld, Jens, Mielke, Thorsten, Berninghausen, Otto, Wilson, Daniel N., Beckmann, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022528/
https://ncbi.nlm.nih.gov/pubmed/21267063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000581
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