טוען...
CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides
Ribosome stalling leads to recruitment of the Ribosome Quality control Complex (RQC), which targets the partially synthesized polypeptide for proteasomal degradation through the action of the ubiquitin ligase Ltn1p. A second core RQC component, Rqc2p, modifies the nascent polypeptide by adding a Car...
שמור ב:
| הוצא לאור ב: | Science |
|---|---|
| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5673106/ https://ncbi.nlm.nih.gov/pubmed/28751611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aam7787 |
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