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Pyrrolysine analogues as substrates for pyrrolysyl-tRNA synthetase
In certain methanogenic archaea a new amino acid, pyrrolysine (Pyl), is inserted at in-frame UAG codons in the mRNAs of some methyltransferases. Pyl is directly acylated onto a suppressor tRNA(Pyl) by pyrrolysyl-tRNA synthetase (PylRS). Due to the lack of a readily available Pyl source, we looked fo...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1817836/ https://ncbi.nlm.nih.gov/pubmed/17126325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2006.11.028 |
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