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An aminoacyl-tRNA synthetase that specifically activates pyrrolysine

Pyrrolysine, the 22nd cotranslationally inserted amino acid, was found in the Methanosarcina barkeri monomethylamine methyltransferase protein in a position that is encoded by an in-frame UAG stop codon in the mRNA. M. barkeri encodes a special amber suppressor tRNA (tRNA(Pyl)) that presumably recog...

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Autores principales: Polycarpo, Carla, Ambrogelly, Alexandre, Bérubé, Amélie, Winbush, SusAnn M., McCloskey, James A., Crain, Pamela F., Wood, John L., Söll, Dieter
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC515082/
https://ncbi.nlm.nih.gov/pubmed/15314242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405362101
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