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Misacylation of pyrrolysine tRNA in vitro and in vivo

Methanosarcina barkeri inserts pyrrolysine (Pyl) at an in-frame UAG codon in its monomethylamine methyltransferase gene. Pyrrolysyl-tRNA synthetase acylates Pyl onto tRNA(Pyl), the amber suppressor pyrrolysine tRNA. Here we show that M. barkeri Fusaro tRNA(Pyl) can be misacylated with serine by the...

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Auteurs principaux: Gundllapalli, Sarath, Ambrogelly, Alexandre, Umehara, Takuya, Li, Darrick, Polycarpo, Carla, Söll, Dieter
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577721/
https://ncbi.nlm.nih.gov/pubmed/18775710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.08.027
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