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Pyrrolysine is not hardwired for cotranslational insertion at UAG codons
Pyrrolysine (Pyl), the 22nd naturally encoded amino acid, gets acylated to its distinctive UAG suppressor tRNA(Pyl) by the cognate pyrrolysyl-tRNA synthetase (PylRS). Here we determine the RNA elements required for recognition and aminoacylation of tRNA(Pyl) in vivo by using the Pyl analog N-ε-cyclo...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1805618/ https://ncbi.nlm.nih.gov/pubmed/17360621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611634104 |
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