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Rhomboid cleaves Star to regulate the levels of secreted Spitz
Intracellular trafficking of the precursor of Spitz (Spi), the major Drosophila EGF receptor (EGFR) ligand, is facilitated by the chaperone Star, a type II transmembrane protein. This study identifies a novel mechanism for modulating the activity of Star, thereby influencing the levels of active Spi...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1817629/ https://ncbi.nlm.nih.gov/pubmed/17304216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601581 |
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