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Drosophila EGFR signalling is modulated by differential compartmentalization of Rhomboid intramembrane proteases
We explore the role of differential compartmentalization of Rhomboid (Rho) proteases that process the Drosophila EGF receptor ligands, in modulating the amount of secreted ligand and consequently the level of EGF receptor (EGFR) activation. The mSpitz ligand precursor is retained in the ER, and is t...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2367402/ https://ncbi.nlm.nih.gov/pubmed/18369317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.58 |
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