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Drosophila EGFR signalling is modulated by differential compartmentalization of Rhomboid intramembrane proteases
We explore the role of differential compartmentalization of Rhomboid (Rho) proteases that process the Drosophila EGF receptor ligands, in modulating the amount of secreted ligand and consequently the level of EGF receptor (EGFR) activation. The mSpitz ligand precursor is retained in the ER, and is t...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group
2008
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2367402/ https://ncbi.nlm.nih.gov/pubmed/18369317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.58 |
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