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Structural basis for intramembrane proteolysis by rhomboid serine proteases
Intramembrane proteases catalyze peptide bond cleavage of integral membrane protein substrates. This activity is crucial for many biological and pathological processes. Rhomboids are evolutionarily widespread intramembrane serine proteases. Here, we present the 2.3-Å-resolution crystal structure of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1766407/ https://ncbi.nlm.nih.gov/pubmed/17190827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609773104 |
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