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Core principles of intramembrane proteolysis: comparison of rhomboid and site-2 family proteases
Cleavage of proteins within their membrane-spanning segments is an ancient regulatory mechanism that has evolved to control a myriad of cellular processes in all forms of life. Although three mechanistic families of enzymes have been discovered that catalyze hydrolysis within the water-excluding env...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572676/ https://ncbi.nlm.nih.gov/pubmed/18440799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2008.03.005 |
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