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Core principles of intramembrane proteolysis: comparison of rhomboid and site-2 family proteases

Cleavage of proteins within their membrane-spanning segments is an ancient regulatory mechanism that has evolved to control a myriad of cellular processes in all forms of life. Although three mechanistic families of enzymes have been discovered that catalyze hydrolysis within the water-excluding env...

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Detalhes bibliográficos
Main Authors: Urban, Sinisa, Shi, Yigong
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572676/
https://ncbi.nlm.nih.gov/pubmed/18440799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2008.03.005
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