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Drosophila EGFR signalling is modulated by differential compartmentalization of Rhomboid intramembrane proteases

We explore the role of differential compartmentalization of Rhomboid (Rho) proteases that process the Drosophila EGF receptor ligands, in modulating the amount of secreted ligand and consequently the level of EGF receptor (EGFR) activation. The mSpitz ligand precursor is retained in the ER, and is t...

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Detaylı Bibliyografya
Asıl Yazarlar: Yogev, Shaul, Schejter, Eyal D, Shilo, Ben-Zion
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367402/
https://ncbi.nlm.nih.gov/pubmed/18369317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.58
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