Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz

Spitz (Spi) is a TGFα homolog that is a cardinal ligand for the Drosophila EGF receptor throughout development. Cleavage of the ubiquitously expressed transmembrane form of Spi (mSpi) precedes EGF receptor activation. We show that the Star and Rhomboid (Rho) proteins are necessary for Spi cleavage i...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Tsruya, Rachel, Schlesinger, Ayelet, Reich, Aderet, Gabay, Limor, Sapir, Amir, Shilo, Ben-Zion
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2002
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11799065/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.214202
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!