Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz
Spitz (Spi) is a TGFα homolog that is a cardinal ligand for the Drosophila EGF receptor throughout development. Cleavage of the ubiquitously expressed transmembrane form of Spi (mSpi) precedes EGF receptor activation. We show that the Star and Rhomboid (Rho) proteins are necessary for Spi cleavage i...
Kaydedildi:
| Yayımlandı: | Genes Dev |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2002
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11799065/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.214202 |
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