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Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-α homolog Spitz

Activation of the Drosophila epidermal growth factor receptor (DER) by the transmembrane ligand, Spitz (Spi), requires two additional transmembrane proteins, Rhomboid and Star. Genetic evidence suggests that Rhomboid and Star facilitate DER signaling by processing membrane-bound Spi (mSpi) to an act...

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Detalles Bibliográficos
Main Authors: Bang, Anne G., Kintner, Chris
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC316351/
https://ncbi.nlm.nih.gov/pubmed/10652272
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