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Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage

Spitz (Spi) is the most prominent ligand of the Drosophila EGF receptor (DER). It is produced as an inactive membrane precursor which is retained in the endoplasmic reticulum (ER). To allow cleavage, Star transports Spi to the Golgi, where it undergoes cleavage by Rhomboid (Rho). Since some DER phen...

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Detalhes bibliográficos
Main Authors: Reich, Aderet, Shilo, Ben-Zion
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126175/
https://ncbi.nlm.nih.gov/pubmed/12169631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf439
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