Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage
Spitz (Spi) is the most prominent ligand of the Drosophila EGF receptor (DER). It is produced as an inactive membrane precursor which is retained in the endoplasmic reticulum (ER). To allow cleavage, Star transports Spi to the Golgi, where it undergoes cleavage by Rhomboid (Rho). Since some DER phen...
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| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2002
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126175/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12169631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf439 |
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