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Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage

Spitz (Spi) is the most prominent ligand of the Drosophila EGF receptor (DER). It is produced as an inactive membrane precursor which is retained in the endoplasmic reticulum (ER). To allow cleavage, Star transports Spi to the Golgi, where it undergoes cleavage by Rhomboid (Rho). Since some DER phen...

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Bibliografiske detaljer
Main Authors: Reich, Aderet, Shilo, Ben-Zion
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC126175/
https://ncbi.nlm.nih.gov/pubmed/12169631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf439
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