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Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage

Spitz (Spi) is the most prominent ligand of the Drosophila EGF receptor (DER). It is produced as an inactive membrane precursor which is retained in the endoplasmic reticulum (ER). To allow cleavage, Star transports Spi to the Golgi, where it undergoes cleavage by Rhomboid (Rho). Since some DER phen...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Reich, Aderet, Shilo, Ben-Zion
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC126175/
https://ncbi.nlm.nih.gov/pubmed/12169631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf439
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