A Phenylalanine Clamp Catalyzes Protein Translocation Through the Anthrax Toxin Pore

The protective antigen component of anthrax toxin forms a homoheptameric pore in the endosomal membrane, creating a narrow passageway for the enzymatic components of the toxin to enter the cytosol. We found that, during conversion of the heptameric precursor to the pore, the seven phenylalanine-427...

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Bibliografiske detaljer
Main Authors: Krantz, Bryan A., Melnyk, Roman A., Zhang, Sen, Juris, Stephen J., Lacy, D. Borden, Wu, Zhengyan, Finkelstein, Alan, Collier, R. John
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1815389/
https://ncbi.nlm.nih.gov/pubmed/16051798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1113380
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