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Peptide- and proton-driven allosteric clamps catalyze anthrax toxin translocation across membranes

Anthrax toxin is an intracellularly acting toxin in which sufficient information is available regarding the structure of its transmembrane channel, allowing for detailed investigation of models of translocation. Anthrax toxin, comprising three proteins—protective antigen (PA), lethal factor (LF), an...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Das, Debasis, Krantz, Bryan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003235/
https://ncbi.nlm.nih.gov/pubmed/27506790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600624113
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