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Charge Requirements for Proton Gradient-driven Translocation of Anthrax Toxin
Anthrax lethal toxin is used as a model system to study protein translocation. The toxin is composed of a translocase channel, called protective antigen (PA), and an enzyme, called lethal factor (LF). A proton gradient (ΔpH) can drive LF unfolding and translocation through PA channels; however, the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3123086/ https://ncbi.nlm.nih.gov/pubmed/21507946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.231167 |
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