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Lethal factor unfolding is the most force-dependent step of anthrax toxin translocation

Cellular compartmentalization requires machinery capable of translocating polypeptides across membranes. In many cases, transported proteins must first be unfolded by means of the proton motive force and/or ATP hydrolysis. Anthrax toxin, which is composed of a channel-forming protein and two substra...

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Detalhes bibliográficos
Main Authors: Thoren, Katie L., Worden, Evan J., Yassif, Jaime M., Krantz, Bryan A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779827/
https://ncbi.nlm.nih.gov/pubmed/19926859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905880106
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