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Anthrax toxin translocation complex reveals insight into the lethal factor unfolding and refolding mechanism

Translocation is essential to the anthrax toxin mechanism. Protective antigen (PA), the binding component of this AB toxin, forms an oligomeric pore that translocates lethal factor (LF) or edema factor, the active components of the toxin, into the cell. Structural details of the translocation proces...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Machen, Alexandra J., Fisher, Mark T., Freudenthal, Bret D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219829/
https://ncbi.nlm.nih.gov/pubmed/34158520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91596-3
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