Dynamic Phenylalanine Clamp Interactions Define Single-Channel Polypeptide Translocation through the Anthrax Toxin Protective Antigen Channel

Anthrax toxin is an intracellularly acting toxin where sufficient detail is known about the structure of its channel, allowing for molecular investigations of translocation. The toxin is composed of three proteins, protective antigen (PA), lethal factor (LF), and edema factor (EF). The toxin’s trans...

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Gepubliceerd in:J Mol Biol
Hoofdauteurs: Ghosal, Koyel, Colby, Jennifer M., Das, Debasis, Joy, Stephen T., Arora, Paramjit S., Krantz, Bryan A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562545/
https://ncbi.nlm.nih.gov/pubmed/28192089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.02.005
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