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Dynamic Phenylalanine Clamp Interactions Define Single-Channel Polypeptide Translocation through the Anthrax Toxin Protective Antigen Channel

Anthrax toxin is an intracellularly acting toxin where sufficient detail is known about the structure of its channel, allowing for molecular investigations of translocation. The toxin is composed of three proteins, protective antigen (PA), lethal factor (LF), and edema factor (EF). The toxin’s trans...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Ghosal, Koyel, Colby, Jennifer M., Das, Debasis, Joy, Stephen T., Arora, Paramjit S., Krantz, Bryan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562545/
https://ncbi.nlm.nih.gov/pubmed/28192089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.02.005
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