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A Phenylalanine Clamp Catalyzes Protein Translocation Through the Anthrax Toxin Pore
The protective antigen component of anthrax toxin forms a homoheptameric pore in the endosomal membrane, creating a narrow passageway for the enzymatic components of the toxin to enter the cytosol. We found that, during conversion of the heptameric precursor to the pore, the seven phenylalanine-427...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1815389/ https://ncbi.nlm.nih.gov/pubmed/16051798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1113380 |
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