Protein Translocation through Anthrax Toxin Channels Formed in Planar Lipid Bilayers

The 63-kDa fragment of the protective antigen (PA) component of anthrax toxin forms a heptameric channel, (PA(63))(7), in acidic endosomal membranes that leads to the translocation of edema factor (EF) and lethal factor (LF) to the cytosol. It also forms a channel in planar phospholipid bilayer memb...

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Bibliographic Details
Main Authors: Zhang, Sen, Udho, Eshwar, Wu, Zhengyan, Collier, R. John, Finkelstein, Alan
Format: Artigo
Language:Inglês
Published: Biophysical Society 2004
Subjects:
Channels, Receptors, and Electrical Signaling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304895/
https://ncbi.nlm.nih.gov/pubmed/15377524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.050864
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