Llwytho...

A loop network within the anthrax toxin pore positions the phenylalanine clamp in an active conformation

Heptameric pores formed in the endosomal membrane by the protective antigen moiety of anthrax toxin serve as portals for entry of the enzymatic moieties of the toxin into the cytosol. In the aqueous lumen of each pore is a “Phe clamp,” a heptad of narrowly apposed Phe residues (Phe-427), that cataly...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Melnyk, Roman A., Collier, R. John
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479862/
https://ncbi.nlm.nih.gov/pubmed/16785422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604000103
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