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Dendritic cells with TGF-β1 differentiate naïve CD4(+)CD25(−) T cells into islet-protective Foxp3(+) regulatory T cells
CD4(+)CD25(+)Foxp3(+) regulatory T cells (T regs) are important for preventing autoimmune diabetes and are either thymic-derived (natural) or differentiated in the periphery outside the thymus (induced). Here we show that β-cell peptide-pulsed dendritic cells (DCs) from nonobese diabetic (NOD) mice...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1815265/ https://ncbi.nlm.nih.gov/pubmed/17307871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611646104 |
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