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Rapamycin-Conditioned Donor Dendritic Cells Differentiate CD4(+)CD25(+)Foxp3(+) T Cells In Vitro with TGF-β 1 for Islet Transplantation

Dendritic cells (DCs) conditioned with the mammalian target of rapamycin (mTOR) inhibitor rapamycin have been previously shown to expand naturally existing regulatory T cells (nTregs). This work addresses whether rapamycin-conditioned donor DCs could effectively induce CD4(+)CD25(+)Foxp3(+) Tregs (i...

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Bibliografische gegevens
Hoofdauteurs: Pothoven, K. L., Kheradmand, T., Yang, Q., Houlihan, J. L., Zhang, H., DeGutes, M., Miller, S. D., Luo, X.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995630/
https://ncbi.nlm.nih.gov/pubmed/20626386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2010.03199.x
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