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Rapamycin-Conditioned Donor Dendritic Cells Differentiate CD4(+)CD25(+)Foxp3(+) T Cells In Vitro with TGF-β 1 for Islet Transplantation
Dendritic cells (DCs) conditioned with the mammalian target of rapamycin (mTOR) inhibitor rapamycin have been previously shown to expand naturally existing regulatory T cells (nTregs). This work addresses whether rapamycin-conditioned donor DCs could effectively induce CD4(+)CD25(+)Foxp3(+) Tregs (i...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3995630/ https://ncbi.nlm.nih.gov/pubmed/20626386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2010.03199.x |
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