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Donor-specific CD8(+)Foxp3(+) T cells protect skin allografts and facilitate induction of conventional CD4(+)Foxp3(+) regulatory T cells
CD4(+) regulatory T cells play a critical role in tolerance induction in transplantation. CD8(+) suppressor T cells have also been shown to control alloimmune responses in pre-clinical and clinical models. However, the exact nature of the CD8(+) suppressor T cells, their induction and mechanism of f...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429694/ https://ncbi.nlm.nih.gov/pubmed/22681667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.04120.x |
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