Donor-specific CD8(+)Foxp3(+) T cells protect skin allografts and facilitate induction of conventional CD4(+)Foxp3(+) regulatory T cells

CD4(+) regulatory T cells play a critical role in tolerance induction in transplantation. CD8(+) suppressor T cells have also been shown to control alloimmune responses in pre-clinical and clinical models. However, the exact nature of the CD8(+) suppressor T cells, their induction and mechanism of f...

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Hlavní autoři: Lerret, Nadine M., Houlihan, Josetta L., Kheradmand, Taba, Pothoven, Kathryn L., Zhang, Zheng J., Luo, Xunrong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429694/
https://ncbi.nlm.nih.gov/pubmed/22681667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.04120.x
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