Effective expansion of alloantigen-specific Foxp3(+) CD25(+) CD4(+) regulatory T cells by dendritic cells during the mixed leukocyte reaction

Thymic-derived CD25(+) CD4(+) T regulatory cells (Tregs) suppress immune responses, including transplantation. Here we evaluated the ability of dendritic cells (DCs) to expand alloantigen-specific Tregs in the mixed leukocyte reaction (MLR) that develops from polyclonal populations of T cells. The a...

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Detalhes bibliográficos
Main Authors: Yamazaki, Sayuri, Patel, Munjal, Harper, Alice, Bonito, Anthony, Fukuyama, Hidehiro, Pack, Maggi, Tarbell, Kristin V., Talmor, Mia, Ravetch, Jeffrey V., Inaba, Kayo, Steinman, Ralph M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413800/
https://ncbi.nlm.nih.gov/pubmed/16473944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510606103
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