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Direct Expansion of Functional CD25(+) CD4(+) Regulatory T Cells by Antigen-processing Dendritic Cells

An important pathway for immune tolerance is provided by thymic-derived CD25(+) CD4(+) T cells that suppress other CD25(−) autoimmune disease–inducing T cells. The antigen-presenting cell (APC) requirements for the control of CD25(+) CD4(+) suppressor T cells remain to be identified, hampering their...

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Detalhes bibliográficos
Main Authors: Yamazaki, Sayuri, Iyoda, Tomonori, Tarbell, Kristin, Olson, Kara, Velinzon, Klara, Inaba, Kayo, Steinman, Ralph M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194081/
https://ncbi.nlm.nih.gov/pubmed/12874257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030422
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