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Prion species barrier between the closely related yeast proteins is detected despite coaggregation
Prions are self-perpetuating and, in most cases, aggregation-prone protein isoforms that transmit neurodegenerative diseases in mammals and control heritable traits in yeast. Prion conversion requires a very high level of identity of the interacting protein sequences. Decreased transmission of the p...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1815260/ https://ncbi.nlm.nih.gov/pubmed/17296932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611158104 |
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