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Proteolysis suppresses spontaneous prion generation in yeast
Prions are infectious proteins that cause fatal neurodegenerative disorders including Creutzfeldt–Jakob and bovine spongiform encephalopathy (mad cow) diseases. The yeast [PSI(+)] prion is formed by the translation-termination factor Sup35, is the best-studied prion, and provides a useful model syst...
Uloženo v:
| Vydáno v: | J Biol Chem |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5724000/ https://ncbi.nlm.nih.gov/pubmed/29038292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.811323 |
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