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Comparison of siRNA-induced off-target RNA and protein effects
The downregulation of many mRNAs has been observed through bioinformatic analysis of microarray results following transfection of short interfering RNAs (siRNAs). Many of these mRNA changes are due to the interaction of the siRNA guide strand with partially complementary sites and thus are considere...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1800510/ https://ncbi.nlm.nih.gov/pubmed/17237357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.352507 |
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