Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function

One form of juvenile onset autosomal recessive amyotrophic lateral sclerosis (ALS2) has been linked to the dysfunction of the ALS2 gene. The ALS2 gene is expressed in lymphoblasts, however, whether ALS2-deficiency affects periphery blood is unclear. Here we report that ALS2 knockout (ALS2(−/−)) mice...

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Detalhes bibliográficos
Main Authors: Erie, Elizabeth A., Shim, Hoon, Smith, Aleah L., Lin, Xian, Keyvanfar, Keyvan, Xie, Chengsong, Chen, Jichun, Cai, Huaibin
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796843/
https://ncbi.nlm.nih.gov/pubmed/17156857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2006.10.019
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