ALS2/Alsin Knockout Mice and Motor Neuron Diseases

Autosomal recessive mutations in the ALS2 gene have been linked to juvenile-onset amyotrophic lateral sclerosis (ALS2), primary lateral sclerosis and juvenile-onset ascending hereditary spastic paraplegia. Except for two recently identified missense mutations, all other mutations in the ALS2 gene le...

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Detalhes bibliográficos
Main Authors: Cai, Huaibin, Shim, Hoon, Lai, Chen, Xie, Chengsong, Lin, Xian, Yang, Wan Jou, Chandran, Jayanth
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2008
Assuntos:
Modeling Neurodegenerative Diseases in vivo
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556598/
https://ncbi.nlm.nih.gov/pubmed/18714162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000151295
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