Loss of ALS2 Function Is Insufficient to Trigger Motor Neuron Degeneration in Knock-Out Mice But Predisposes Neurons to Oxidative Stress

Amyotrophic lateral sclerosis (ALS), the most common motor neuron disease, is caused by a selective loss of motor neurons in the CNS. Mutations in the ALS2 gene have been linked to one form of autosomal recessive juvenile onset ALS (ALS2). To investigate the pathogenic mechanisms of ALS2, we generat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cai, Huaibin, Lin, Xian, Xie, Chengsong, Laird, Fiona M., Lai, Chen, Wen, Hongjin, Chiang, Hsueh-Cheng, Shim, Hoon, Farah, Mohamed H., Hoke, Ahmet, Price, Donald L., Wong, Philip C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364727/
https://ncbi.nlm.nih.gov/pubmed/16107644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1645-05.2005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados