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Androgen receptor decoy molecules block the growth of prostate cancer
The androgen receptor (AR) is activated by both ligand-dependent and -independent mechanisms. Current therapies for prostate cancer target the ligand-binding domain in the C terminus of the AR. However, ligand-independent activation of the AR occurs by the N-terminal domain (NTD), making the NTD a p...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783142/ https://ncbi.nlm.nih.gov/pubmed/17227854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606718104 |
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