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14-3-3 sigma increases the transcriptional activity of the androgen receptor in the absence of androgens

The androgen receptor (AR) is a ligand-activated transcription factor that regulates numerous target genes, including prostate specific antigen (PSA). We examined the ability of each member of the 14-3-3 family to modulate transcription of PSA through the AR. Despite significant homology within the...

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Detalhes bibliográficos
Main Authors: Quayle, Steven N., Sadar, Marianne D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040346/
https://ncbi.nlm.nih.gov/pubmed/17433535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2007.03.003
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