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Androgen receptor and its splice variants in prostate cancer
Androgen receptor (AR) is a transcription factor that becomes active upon binding to androgens via its ligand-binding domain (LBD) or in response to signaling cascades initiated by growth factors and cytokines. The activity of AR requires regions within the N-terminal domain (NTD) in a manner that i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729216/ https://ncbi.nlm.nih.gov/pubmed/21748469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-011-0766-7 |
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