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An imaging agent to detect androgen receptor and its active splice variants in prostate cancer
Constitutively active splice variants of androgen receptor (AR-Vs) lacking ligand-binding domain (LBD) are a mechanism of resistance to androgen receptor LBD–targeted (AR LBD–targeted) therapies for metastatic castration-resistant prostate cancer (CRPC). There is a strong unmet clinical need to iden...
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| 出版年: | JCI Insight |
|---|---|
| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980083/ https://ncbi.nlm.nih.gov/pubmed/27525313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87850 |
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